The Masquelet technique has become increasingly popular in reconstruction scenarios such as osteomyelitis, cancer, and nonunions. The procedure is a two-staged approach: first, a polymethylmethacrylate (PMMA) cement spacer is inserted to fill a bone void. The spacer induces a membrane to form around it, and 6-9 weeks later, the second stage involves carefully extracting the spacer and filling the membrane with bone graft. Most of the current literature has published either femoral or tibial involvement for Masquelet studies, with limited published data on foot reconstruction. Here, the authors used the procedure for the fourth metatarsal. Despite complications, this case proves a more excellent utility and warrants further investigation into Masquelet techniques in the foot.
Fowler KA, Dahlberg LL, Haileyesus T, Annest JL. Firearm injuries in the United States. Prev Med. 2015 Oct;79:5-14. doi: 10.1016/j.ypmed.2015.06.002. Epub 2015 Jun 24. PMID: 26116133; PMCID: PMC4700838.
Cook A, Osler T, Hosmer D, Glance L, Rogers F, Gross B, Garcia-Filion P, Malhotra A. Gunshot wounds resulting in hospitalization in the United States: 2004-2013. Injury. 2017 Mar;48(3):621-627. doi: 10.1016/j.injury.2017.01.044. Epub 2017 Jan 30. PMID: 28173921..
Bartlett CS, Helfet DL, Hausman MR, Strauss E. Ballistics and gunshot wounds: effects on musculoskeletal tissues. J Am Acad Orthop Surg. 2000 Jan-Feb;8(1):21-36. doi: 10.5435/00124635-200001000-00003. PMID: 10666650.
Gouron R. Surgical technique and indications of the induced membrane procedure in children. Orthop Traumatol Surg Res. 2016 Feb;102(1 Suppl):S133-9. doi: 10.1016/j.otsr.2015.06.027. Epub 2016 Jan 7. PMID: 26774902.
Stafford PR, Norris BL. Reamer-irrigator-aspirator bone graft and bi Masquelet technique for segmental bone defect nonunions: a review of 25 cases. Injury. 2010 Nov;41 Suppl 2:S72-7. doi: 10.1016/S0020-1383(10)70014-0. PMID: 21144933.
Morris R, Hossain M, Evans A, Pallister I. Induced membrane technique for treating tibial defects gives mixed results. Bone Joint J. 2017 May;99-B(5):680-685. doi: 10.1302/0301-620X.99B5.BJJ-2016-0694.R2. PMID: 28455479.
Abdellaoui H, Atarraf K, Chater L, Afifi MA. Congenital pseudarthrosis of the clavicle treated by Masquelet technique. BMJ Case Rep. 2017 Nov 8;2017:bcr2017221557. doi: 10.1136/bcr-2017-221557. PMID: 29122899; PMCID: PMC5695429.
Calori GM, Mazza EL, Colombo A, Mazzola S, Colombo M. Treatment of an atrophic clavicle non-union with the chamber induction technique: a case report. Injury. 2017 Oct;48 Suppl 3:S71-S75. doi: 10.1016/S0020-1383(17)30662-9. PMID: 29025615.
Morelli I, Drago L, George DA, Romanò D, Romanò CL. Managing large bone defects in children: a systematic review of the 'induced membrane technique'. J Pediatr Orthop B. 2018 Sep;27(5):443-455. doi: 10.1097/BPB.0000000000000456. PMID: 28368930.
Konda SR, Gage M, Fisher N, Egol KA. Segmental Bone Defect Treated With the Induced Membrane Technique. J Orthop Trauma. 2017 Aug;31 Suppl 3:S21-S22. doi: 10.1097/BOT.0000000000000899. PMID: 28697078.
Tong K, Zhong Z, Peng Y, Lin C, Cao S, Yang Y, Wang G. Masquelet technique versus Ilizarov bone transport for reconstruction of lower extremity bone defects following posttraumatic osteomyelitis. Injury. 2017 Jul;48(7):1616-1622. doi: 10.1016/j.injury.2017.03.042. Epub 2017 Apr 4. PMID: 28408083.
Makridis KG, Theocharakis S, Fragkakis EM, Giannoudis PV. Reconstruction of an extensive soft tissue and bone defect of the first metatarsal with the use of Masquelet technique: a case report. Foot Ankle Surg. 2014 Jun;20(2):e19-22. doi: 10.1016/j.fas.2013.11.006. Epub 2013 Dec 16. PMID: 24796840.
Zoller SD, Cao LA, Smith RA, Sheppard W, Lord EL, Hamad CD, Ghodasra JH, Lee C, Jeffcoat D. Staged reconstruction of diaphyseal fractures with segmental defects: Surgical and patient-reported outcomes. Injury. 2017 Oct;48(10):2248-2252. doi: 10.1016/j.injury.2017.06.018. Epub 2017 Jun 23. PMID: 28712488.
Liu F, Huang RK, Xie M, Pan H, Zhao JJ, Lei B. Use of Masquelet's technique for treating the first metatarsophalangeal joint in cases of gout combined with a massive bone defect. Foot Ankle Surg. 2018 Apr;24(2):159-163. doi: 10.1016/j.fas.2017.01.009. Epub 2017 Feb 17. PMID: 29409218.
Pelissier P, Bollecker V, Martin D, Baudet J. Reconstruction du pied par la technique "bi-Masquelet" [Foot reconstruction with the "bi-Masquelet" procedure]. Ann Chir Plast Esthet. 2002 Aug;47(4):304-7. French. doi: 10.1016/s0294-1260(02)00123-1. PMID: 12420622.
Largey A, Faline A, Hebrard W, Hamoui M, Canovas F. Management of massive traumatic compound defects of the foot. Orthop Traumatol Surg Res. 2009 Jun;95(4):301-4. doi: 10.1016/j.otsr.2009.02.005. Epub 2009 May 12. PMID: 19442599.
Moghaddam A, Zietzschmann S, Bruckner T, Schmidmaier G. Treatment of atrophic tibia non-unions according to 'diamond concept': Results of one- and two-step treatment. Injury. 2015 Oct;46 Suppl 4:S39-50. doi: 10.1016/S0020-1383(15)30017-6. PMID: 26542865.
Giannoudis PV, Faour O, Goff T, Kanakaris N, Dimitriou R. Masquelet technique for the treatment of bone defects: tips-tricks and future directions. Injury. 2011 Jun;42(6):591-8. doi: 10.1016/j.injury.2011.03.036. Epub 2011 May 4. PMID: 21543068.
Micev AJ, Kalainov DM, Soneru AP. Masquelet technique for treatment of segmental bone loss in the upper extremity. J Hand Surg Am. 2015 Mar;40(3):593-8. doi: 10.1016/j.jhsa.2014.12.007. Epub 2015 Jan 31. PMID: 25648786.
Apard T, Bigorre N, Cronier P, Duteille F, Bizot P, Massin P. Two-stage reconstruction of post-traumatic segmental tibia bone loss with nailing. Orthop Traumatol Surg Res. 2010 Sep;96(5):549-53. doi: 10.1016/j.otsr.2010.02.010. Epub 2010 Jun 4. PMID: 20605548.
Flamans B, Pauchot J, Petite H, Blanchet N, Rochet S, Garbuio P, Tropet Y, Obert L. Pertes de substance osseuse à la main et au poignet traitées en urgence par technique de la membrane induite (technique de Masquelet) [Use of the induced membrane technique for the treatment of bone defects in the hand or wrist, in emergency]. Chir Main. 2010 Oct;29(5):307-14. French. doi: 10.1016/j.main.2010.06.008. Epub 2010 Jul 24. PMID: 20728395.
Jiang N, Qin CH, Ma YF, Wang L, Yu B. Possibility of one-stage surgery to reconstruct bone defects using the modified Masquelet technique with degradable calcium sulfate as a cement spacer: A case report and hypothesis. Biomed Rep. 2016 Mar;4(3):374-378. doi: 10.3892/br.2016.584. Epub 2016 Jan 27. PMID: 26998279; PMCID: PMC4774369.
Gaio N, Martino A, Toth Z, Watson JT, Nicolaou D, McBride-Gagyi S. Masquelet technique: The effect of altering implant material and topography on membrane matrix composition, mechanical and barrier properties in a rat defect model. J Biomech. 2018 Apr 27;72:53-62. doi: 10.1016/j.jbiomech.2018.02.026. Epub 2018 Feb 27. PMID: 29510858; PMCID: PMC5895482.
Salgado CJ, Lin CH, Fuller DA, Duncan AN, Camison L, Mardini S. Foot salvage after loss of the first and second metatarsal rays with a free fibular osteocutaneous flap. J Am Podiatr Med Assoc. 2011 Nov-Dec;101(6):531-6. doi: 10.7547/1010531. PMID: 22106202.
Raja Kummoona*Raja Kummoona*. Kummoona Chondro-Ossous Graft for Reconstruction of the Temporomandibular Joint in Children. . 2017 doi: 10.29328/journal.aceo.1001001; 1: 001-003
Amelia Carr, Saso Ivanovski, Randy Bindra and Cedryck Vaquette*Amelia Carr,Saso Ivanovski,Randy Bindra,Cedryck Vaquette*. What is the future for Scapholunate interosseous ligament reconstruction?. . 2018 doi: 10.29328/journal.aceo.1001004; 2: 004-007
Castagno C*, Campano D, Fernandez I and Weiss WMCastagno C*, Campano D, Fernandez I, Weiss WM. Masquelet Technique for Reconstruction of a Fourth Metatarsal Defect Following a Low-velocity Gunshot Wound: A Case Report. . 2023 doi: 10.29328/journal.aceo.1001017; 7: 022-026
Bijaya Bhusal*Bijaya Bhusal*. Poor Diet Leading to the Increasing Risk of Atherosclerosis in the World. J Cardiol Cardiovasc Med. 2024: doi: 10.29328/journal.jccm.1001195; 9: 142-147
Abdulhamit Taha Koca, Mustafa Bayhan, Yunus Ayberk Demir and Ayse Zeynep Zengin*Abdulhamit Taha Koca,Mustafa Bayhan,Yunus Ayberk Demir,Ayse Zeynep Zengin*. Awareness and Knowledge of Specialists/Trainers and General Dental Practitioners about Medical-Related Osteonecrosis of the Jaws. J Oral Health Craniofac Sci. 2024: doi: 10.29328/journal.johcs.1001050; 9: 023-031
Andrea Bellone*Andrea Bellone*. Advances in Physiological Research: Consideration on Arterial Hypercapnia in Acute Cardiogenic Pulmonary Edema (ACPE). Arch Case Rep. 2024: doi: 10.29328/journal.acr.1001108; 8: 116-117
H Pérez-Aguilar*, M Lacruz-Asaro and F Arán-AisH Pérez-Aguilar*, M Lacruz-Asaro, F Arán-Ais. Evaluation of Biostimulants Based on Recovered Protein Hydrolysates from Animal By-products as Plant Growth Enhancers. J Plant Sci Phytopathol. 2023 doi: 10.29328/journal.jpsp.1001104; 7: 042-047
Denis Tonini, Kai Wu, Renata Saha and Jian-Ping Wang*Denis Tonini,Kai Wu,Renata Saha,Jian-Ping Wang*. Feasibility study of magnetic sensing for detecting single-neuron action potentials. Ann Biomed Sci Eng. 2022 doi: 10.29328/journal.abse.1001018; 6: 019-029
Julian A Purrinos* and Ramzi YounisJulian A Purrinos*, Ramzi Younis. Sinonasal Myxoma Extending into the Orbit in a 4-Year Old: A Case Presentation. Arch Case Rep. 2024 doi: 10.29328/journal.acr.1001099; 8: 075-077
Khashayar Maroufi*Khashayar Maroufi*. Physical activity can change the physiological and psychological circumstances during COVID-19 pandemic: A narrative review. J Sports Med Ther. 2021 doi: 10.29328/journal.jsmt.1001051; 6: 001-007
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